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Stabilization of a Broadly Neutralizing Anti-Chikungunya Virus Single Domain Antibody

A single domain antibody (clone CC3) previously found to neutralize a vaccine strain of the chikungunya virus (PRNT(50) = 2. 5 ng/mL) was found to be broadly neutralizing. Clone CC3 is not only able to neutralize a wild-type (WT) strain of chikungunya virus (CHIKV), but also neutralizes WT strains o...

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Detalles Bibliográficos
Autores principales: Liu, Jinny L., Webb, Emily M., Zabetakis, Dan, Burke, Crystal W., Gardner, Christina L., Glass, Pamela J., Legler, Patricia M., Weger-Lucarelli, James, Anderson, George P., Goldman, Ellen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876468/
https://www.ncbi.nlm.nih.gov/pubmed/33585527
http://dx.doi.org/10.3389/fmed.2021.626028