PLCγ1 inhibition combined with inhibition of apoptosis and necroptosis increases cartilage matrix synthesis in IL‐1β‐treated rat chondrocytes

Osteoarthritis (OA) is an age‐related, chronic degenerative disease. With the increasing median age of the population, this disease has become an important public health problem. New, disease‐modifying therapies are needed. A potential novel molecular target is phospholipase Cγ1 (PLCγ1), a critical...

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Detalles Bibliográficos
Autores principales: Chen, Xiaolei, Chen, Ri, Xu, Yang, Xia, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876495/
https://www.ncbi.nlm.nih.gov/pubmed/33326693
http://dx.doi.org/10.1002/2211-5463.13064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876495/
https://www.ncbi.nlm.nih.gov/pubmed/33326693
http://dx.doi.org/10.1002/2211-5463.13064

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