Cargando…

Detect it so you can treat it: A case series and proposed checklist to detect neurotoxicity in checkpoint therapy

BACKGROUND: Checkpoint inhibitors show impressive and durable responses in various cancer types and provide new avenues for cancer immunotherapy. However, these drugs have a variety of adverse events. Common autoimmune-related adverse effects include fatigue, hepatitis, skin rash, endocrine deficien...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bolz, Saskia, Ramakrishnan, Thivyah, Fleischer, Michael, Livingstone, Elisabeth, Stolte, Benjamin, Thimm, Andreas, Kizina, Kathrin, Ugurel, Selma, Kleinschnitz, Christoph, Glas, Martin, Zimmer, Lisa, Hagenacker, Tim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876540/ https://www.ncbi.nlm.nih.gov/pubmed/33604462 http://dx.doi.org/10.1016/j.ensci.2021.100324

Ejemplares similares

Neurofilament Heavy Chain and Tau Protein Are Not Elevated in Cerebrospinal Fluid of Adult Patients with Spinal Muscular Atrophy during Loading with Nusinersen
por: Totzeck, Andreas, et al.
Publicado: (2019)

Nusinersen treatment in adult patients with spinal muscular atrophy: a safety analysis of laboratory parameters
por: Stolte, Benjamin, et al.
Publicado: (2021)

Gut bacterial microbiota in patients with myasthenia gravis: results from the MYBIOM study
por: Totzeck, Andreas, et al.
Publicado: (2021)

Clinical Implication of Dosimetry of Computed Tomography- and Fluoroscopy-Guided Intrathecal Therapy With Nusinersen in Adult Patients With Spinal Muscular Atrophy
por: Kizina, Kathrin, et al.
Publicado: (2019)

Assessment of Bulbar Function in Adult Patients with 5q-SMA Type 2 and 3 under Treatment with Nusinersen
por: Brakemeier, Svenja, et al.
Publicado: (2021)

Metastatic Merkel cell carcinoma and myasthenia gravis: contraindication for therapy with immune checkpoint inhibitors?
por: Zaremba, Anne, et al.
Publicado: (2019)

Cognitive Impairment in Adult Patients with 5q-Associated Spinal Muscular Atrophy
por: Kizina, Kathrin, et al.
Publicado: (2021)

Assessment of Health-Related Quality of Life in Adult Spinal Muscular Atrophy Under Nusinersen Treatment—A Pilot Study
por: Thimm, Andreas, et al.
Publicado: (2022)

Feasibility and safety of intrathecal treatment with nusinersen in adult patients with spinal muscular atrophy
por: Stolte, Benjamin, et al.
Publicado: (2018)

Fatigue in adults with spinal muscular atrophy under treatment with nusinersen
por: Kizina, K., et al.
Publicado: (2020)

Total Plasma Exchange in Neuromuscular Junction Disorders—A Single-Center, Retrospective Analysis of the Efficacy, Safety and Potential Diagnostic Properties in Doubtful Diagnosis
por: Totzeck, Andreas, et al.
Publicado: (2022)

Prevalence of hereditary transthyretin amyloid polyneuropathy in idiopathic progressive neuropathy in conurban areas
por: Thimm, Andreas, et al.
Publicado: (2019)

CIDP, myasthenia gravis, and membranous glomerulonephritis – three autoimmune disorders in one patient: a case report
por: Bolz, Saskia, et al.
Publicado: (2018)

Simultaneous paraneoplastic cerebellar degeneration, Lambert-Eaton syndrome and neuropathy associated with AGNA/anti-SOX1 and VGCC antibodies
por: Feldheim, Jonas, et al.
Publicado: (2021)

Corneal confocal microscopy to detect early immune‐mediated small nerve fibre loss in AL amyloidosis
por: Thimm, Andreas, et al.
Publicado: (2022)

Durable Complete Response in a Melanoma Patient With Unknown Primary, Associated With Sequential and Severe Multi-Organ Toxicity After a Single Dose of CTLA-4 Plus PD-1 Blockade: A Case Report
por: Matull, Johanna, et al.
Publicado: (2020)

So you think you can edit?
por: Budde, Priya Prakash
Publicado: (2014)

Essen transition model for neuromuscular diseases
por: Fleischer, Michael, et al.
Publicado: (2022)

„Essener Transitionsmodell“ bei neuromuskulären Erkrankungen
por: Fleischer, Michael, et al.
Publicado: (2022)

So You Want to be An Oncologist?
por: Hanna, Gerry
Publicado: (2013)

So you want to be an Otorhinolaryngologist?
por: Bell, Philip R
Publicado: (2014)

So You Think You Want to Save the World
por: Bodnar, Benjamin E.
Publicado: (2011)

So you think you can PLS-DA?
por: Ruiz-Perez, Daniel, et al.
Publicado: (2020)

Induction of Survival of Motor Neuron (SMN) Protein Deficiency in Spinal Astrocytes by Small Interfering RNA as an In Vitro Model of Spinal Muscular Atrophy
por: Leo, Markus, et al.
Publicado: (2022)

So you want to be a Nephrologist
por: Maxwell, AP
Publicado: (2010)

So you want to be a Surgeon?
por: Spence, RAJ
Publicado: (2011)

Tonight I need you so
por: Bryson, Jeannie
Publicado: (1994)

So you want to be a Dermatologist
por: Hoey, Susannah
Publicado: (2012)

So you want to be a Paediatrician
por: Lundy, Claire T
Publicado: (2012)

So you want to be a Histopathologist?
por: Houghton, Joe
Publicado: (2013)

So you want to be a Cardiologist
por: Trouton, Tom
Publicado: (2014)

So you want to be a Radiologist?
por: Collins, Anton
Publicado: (2015)

So you want to be an ADEPT Fellow?
por: Donaghy, Grainne, et al.
Publicado: (2016)

So You want to be an Emergency Physician?
por: Maguire, Kevin
Publicado: (2016)

So you want to be an Acute Physician
por: Trimble, Michael
Publicado: (2017)

So you want to be UMJ editor
por: Purvis, John
Publicado: (2019)

As you weed, so shall you reap: on the origin of algaculture in damselfish
por: Aanen, Duur K
Publicado: (2010)

Confidence: transform the way you feel so you can achieve the things you want
por: Yeung, Rob
Publicado: (2013)

Viewpoint : So you want to communicate science?
por: de Jong, Sijbrand
Publicado: (2017)

So you want to be a Medial Student?
por: McLachlan, Gail
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_es25qu9rf6abs92erv59m6ce3s