JNK1 ablation improves pancreatic β‐cell mass and function in db/db diabetic mice without affecting insulin sensitivity and adipose tissue inflammation

The cJun N‐terminal Kinases (JNK) emerged as a major link between obesity and insulin resistance, but their role in the loss of pancreatic β‐cell mass and function driving the progression from insulin resistance to type‐2 diabetes and in the complications of diabetes was not investigated to the same...

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Detalles Bibliográficos
Autores principales: Mazzoli, Arianna, Sardi, Claudia, Breasson, Ludovic, Theilig, Franziska, Becattini, Barbara, Solinas, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876705/
https://www.ncbi.nlm.nih.gov/pubmed/33615154
http://dx.doi.org/10.1096/fba.2020-00081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876705/
https://www.ncbi.nlm.nih.gov/pubmed/33615154
http://dx.doi.org/10.1096/fba.2020-00081

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