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FGFR-TKI resistance in cancer: current status and perspectives

Fibroblast growth factor receptors (FGFRs) play key roles in promoting the proliferation, differentiation, and migration of cancer cell. Inactivation of FGFRs by tyrosine kinase inhibitors (TKI) has achieved great success in tumor-targeted therapy. However, resistance to FGFR-TKI has become a concer...

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Detalles Bibliográficos
Autores principales:	Yue, Sitong, Li, Yukun, Chen, Xiaojuan, Wang, Juan, Li, Meixiang, Chen, Yongheng, Wu, Daichao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876795/ https://www.ncbi.nlm.nih.gov/pubmed/33568192 http://dx.doi.org/10.1186/s13045-021-01040-2

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