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Expression of chondroitin sulfate proteoglycan 4 (CSPG4) in melanoma cells is downregulated upon inhibition of BRAF

Chondroitin sulfate proteoglycan 4 (CSPG4) is a multifunctional transmembrane proteoglycan involved in spreading, migration and invasion of melanoma. In addition to the activating BRAF V600E mutation, CSPG4 was shown to promote MAPK signaling by mediating the growth-factor induced activation of rece...

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Detalles Bibliográficos
Autores principales: Uranowska, Karolina, Kalic, Tanja, Valtsanidis, Veronika, Kitzwögerer, Melitta, Breiteneder, Heimo, Hafner, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876987/
https://www.ncbi.nlm.nih.gov/pubmed/33649790
http://dx.doi.org/10.3892/or.2021.7965