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Modulation of LXR signaling altered the dynamic activity of human colon adenocarcinoma cancer stem cells in vitro

BACKGROUND: The expansion and metastasis of colorectal cancers are closely associated with the dynamic growth of cancer stem cells (CSCs). This study aimed to explore the possible effect of LXR (a regulator of glycolysis and lipid hemostasis) in the tumorgenicity of human colorectal CD133 cells. MET...

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Detalles Bibliográficos
Autores principales: Dianat-Moghadam, Hassan, Khalili, Mostafa, Keshavarz, Mohsen, Azizi, Mehdi, Hamishehkar, Hamed, Rahbarghazi, Reza, Nouri, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877018/
https://www.ncbi.nlm.nih.gov/pubmed/33568147
http://dx.doi.org/10.1186/s12935-021-01803-4