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Secreted frizzled-related protein 5 (SFRP5) protects ATDC5 cells against LPS-induced inflammation and apoptosis via inhibiting Wnt5a/JNK pathway

BACKGROUND: Secreted frizzled-related protein 5 (SFRP5) is an endogenous inhibitor of Wnt5a (wingless-type family member 5a), which has been implicated in anti-inflammatory response. In this study, we aimed to investigate whether SFRP5 could protect chondrocytes against LPS-induced inflammation and...

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Detalles Bibliográficos
Autores principales:	Sun, Minghui, Wang, Weijun, Min, Lingtian, Chen, Cheng, Li, Qing, Weng, Wenjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877043/ https://www.ncbi.nlm.nih.gov/pubmed/33573682 http://dx.doi.org/10.1186/s13018-021-02260-5

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