Inhibition of focal adhesion kinase enhances antitumor response of radiation therapy in pancreatic cancer through CD8+ T cells

OBJECTIVE: Pancreatic ductal adenocarcinoma (PDAC) is a deadly malignancy, due in large part to its resistance to conventional therapies, including radiotherapy (RT). Despite RT exerting a modest antitumor response, it has also been shown to promote an immunosuppressive tumor microenvironment. Previ...

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Detalles Bibliográficos
Autores principales: Osipov, Arsen, Blair, Alex B., Liberto, Juliane, Wang, Jianxin, Li, Keyu, Herbst, Brian, Xu, Yao, Li, Shiqi, Niu, Nan, Rashid, Rufiaat, Ding, Ding, Liu, Yanan, Wang, Zaiqi, Wolfgang, Christopher L., Burkhart, Richard A., Laheru, Daniel, Zheng, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877172/
https://www.ncbi.nlm.nih.gov/pubmed/33628595
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0273

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