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Nobiletin downregulates the SKP2-p21/p27-CDK2 axis to inhibit tumor progression and shows synergistic effects with palbociclib on renal cell carcinoma

OBJECTIVE: Natural extracts, including nobiletin, have been reported to enhance the efficacy and sensitivity of chemotherapeutic drugs. However, whether and how nobiletin affects tumor growth and progression in renal cell carcinoma (RCC) are still unclear. METHODS: Cell proliferation, cell cycle and...

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Detalles Bibliográficos
Autores principales:	Chen, Tingting, Liu, Liu, Zou, Yonghong, Hu, Xiaoyan, Zhang, Wenfeng, Zhou, Tao, Luo, Xi, Fu, Weihua, Xu, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Compuscript 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877181/ https://www.ncbi.nlm.nih.gov/pubmed/33628597 http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0186

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