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Effect of Metformin on Cardiac Metabolism and Longevity in Aged Female Mice

The antidiabetic drug metformin exerts pleiotropic effects on multiple organs, including the cardiovascular system. Evidence has shown that metformin improves healthspan and lifespan in male mice, yet its lifespan lengthening effect in females remains elusive. We herein demonstrated that metformin f...

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Detalles Bibliográficos
Autores principales: Zhu, Xudong, Shen, Weiyan, Liu, Zhu, Sheng, Shihao, Xiong, Wei, He, Ruikun, Zhang, Xuguang, Ma, Likun, Ju, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877555/
https://www.ncbi.nlm.nih.gov/pubmed/33585467
http://dx.doi.org/10.3389/fcell.2020.626011