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Effect of Metformin on Cardiac Metabolism and Longevity in Aged Female Mice
The antidiabetic drug metformin exerts pleiotropic effects on multiple organs, including the cardiovascular system. Evidence has shown that metformin improves healthspan and lifespan in male mice, yet its lifespan lengthening effect in females remains elusive. We herein demonstrated that metformin f...
Autores principales: | Zhu, Xudong, Shen, Weiyan, Liu, Zhu, Sheng, Shihao, Xiong, Wei, He, Ruikun, Zhang, Xuguang, Ma, Likun, Ju, Zhenyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877555/ https://www.ncbi.nlm.nih.gov/pubmed/33585467 http://dx.doi.org/10.3389/fcell.2020.626011 |
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