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Development and evaluation of inhalable composite niclosamide-lysozyme particles: A broad-spectrum, patient-adaptable treatment for coronavirus infections and sequalae
Niclosamide (NIC) has demonstrated promising in vitro antiviral efficacy against SARS-CoV-2, the causative agent of the COVID-19 pandemic. Though NIC is already FDA-approved, administration of the currently available oral formulation results in systemic drug levels that are too low for the inhibitio...
Autores principales: | Brunaugh, Ashlee D., Seo, Hyojong, Warnken, Zachary, Ding, Li, Seo, Sang Heui, Smyth, Hugh D. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877651/ https://www.ncbi.nlm.nih.gov/pubmed/33571320 http://dx.doi.org/10.1371/journal.pone.0246803 |
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