ASC-dependent inflammasomes contribute to immunopathology and mortality in herpes simplex encephalitis

Herpes simplex virus encephalitis (HSE) is the most common cause of sporadic viral encephalitis, and despite targeted antiviral therapy, outcomes remain poor. Although the innate immune system is critical for restricting herpes simplex virus type I (HSV-1) in the brain, there is evidence that prolon...

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Detalles Bibliográficos
Autores principales: Hayes, Cooper K., Wilcox, Douglas R., Yang, Yuchen, Coleman, Grace K., Brown, Melissa A., Longnecker, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877773/
https://www.ncbi.nlm.nih.gov/pubmed/33524073
http://dx.doi.org/10.1371/journal.ppat.1009285

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