Metformin Preconditioning and Postconditioning to Reduce Ischemia Reperfusion Injury in an Isolated Ex Vivo Rat and Porcine Kidney Normothermic Machine Perfusion Model

Metformin may act renoprotective prior to kidney transplantation by reducing ischemia‐reperfusion injury (IRI). This study examined whether metformin preconditioning and postconditioning during ex vivo normothermic machine perfusion (NMP) of rat and porcine kidneys affect IRI. In the rat study, sali...

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Detalles Bibliográficos
Autores principales: Huijink, Tobias M., Venema, Leonie H., Posma, Rene A., de Vries, Nynke J., Westerkamp, Andrie C., Ottens, Petra J., Touw, Daan J., Nijsten, Maarten W., Leuvenink, Henri G.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877823/
https://www.ncbi.nlm.nih.gov/pubmed/32702185
http://dx.doi.org/10.1111/cts.12846

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