A Dynamic Quantitative Systems Pharmacology Model of Inflammatory Bowel Disease: Part 1 – Model Framework

A mechanistic, multistate, mathematical model of inflammatory bowel disease (IBD) was developed by including key biological mechanisms in blood and gut, including cell differentiation, cytokine production, and clinical biomarkers. The model structure is consistent between healthy volunteers and IBD...

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Detalles Bibliográficos
Autores principales: Rogers, Katharine V., Martin, Steven W., Bhattacharya, Indranil, Singh, Ravi Shankar Prasad, Nayak, Satyaprakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877855/
https://www.ncbi.nlm.nih.gov/pubmed/32822108
http://dx.doi.org/10.1111/cts.12849

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