Pharmacogenomics Biomarker Discovery and Validation for Translation in Clinical Practice

Interindividual variability in drug efficacy and toxicity is a major challenge in clinical practice. Variations in drug pharmacokinetics (PKs) and pharmacodynamics (PDs) can be, in part, explained by polymorphic variants in genes encoding drug metabolizing enzymes and transporters (absorption, distr...

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Detalles Bibliográficos
Autores principales: Arbitrio, Mariamena, Scionti, Francesca, Di Martino, Maria Teresa, Caracciolo, Daniele, Pensabene, Licia, Tassone, Pierfrancesco, Tagliaferri, Pierosandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877857/
https://www.ncbi.nlm.nih.gov/pubmed/33089968
http://dx.doi.org/10.1111/cts.12869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877857/
https://www.ncbi.nlm.nih.gov/pubmed/33089968
http://dx.doi.org/10.1111/cts.12869

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