Epigenetic Regulation of Gut Microbial Dysbiosis

Microbiota inside the gut plays a vital role in maintaining human health. Microbial dysbiosis is associated with various complications leading to a range of diseases. Epigenetic changes enforced by various environmental and lifestyle factors lead to heritable modifications. These epigenetic modifica...

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Detalles Bibliográficos
Autores principales: Srivastava, Shivani, Singh, Archana, Sandeep, Kumar, Yadav, Durgavati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877904/
https://www.ncbi.nlm.nih.gov/pubmed/33612870
http://dx.doi.org/10.1007/s12088-021-00920-y
Descripción
Sumario:Microbiota inside the gut plays a vital role in maintaining human health. Microbial dysbiosis is associated with various complications leading to a range of diseases. Epigenetic changes enforced by various environmental and lifestyle factors lead to heritable modifications. These epigenetic modifications include DNA methylation, histone modifications, chromatin remodelling, and ribonucleic acid-based mechanisms. This review summarizes the impacts of environmental factors on the gut microbiome, epigenetic modifications, and their role in cardiovascular diseases.

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