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Crocin Treatment after Maternal Hypoxia Attenuates Spatial Memory Impairment and Expression of BACE1 and HIF-1α in Rat Offspring Brain

INTRODUCTION: Hypoxia via expression of Hypoxia-Inducible Factor-1 (HIF-1) is an important and effective factor in the onset and progression of memory disorders, such as Alzheimer Disease (AD). The activity of β-secretase (BACE1) is increased in hypoxia conditions. BACE1 triggers a cascade of pathol...

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Detalles Bibliográficos
Autores principales:	Fahimi Truski, Fahimeh, Ghotbeddin, Zohreh, Tabandeh, Mohammad Reza, Pourmahdi Borujeni, Mahdi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Iranian Neuroscience Society 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878043/ https://www.ncbi.nlm.nih.gov/pubmed/33613888 http://dx.doi.org/10.32598/bcn.11.4.1787.1

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