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Microscopic Tumour Classification by Digital Mammography

In this paper, we investigate the classification of microscopic tumours using full digital mammography images. Firstly, to address the shortcomings of traditional image segmentation methods, two different deep learning methods are designed to achieve the segmentation of uterine fibroids. The deep la...

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Autores principales: Yang, Jingjing, Li, Huichao, Shi, Ning, Zhang, Qifan, Liu, Yanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878100/
https://www.ncbi.nlm.nih.gov/pubmed/33613927
http://dx.doi.org/10.1155/2021/6635947
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author Yang, Jingjing
Li, Huichao
Shi, Ning
Zhang, Qifan
Liu, Yanan
author_facet Yang, Jingjing
Li, Huichao
Shi, Ning
Zhang, Qifan
Liu, Yanan
author_sort Yang, Jingjing
collection PubMed
description In this paper, we investigate the classification of microscopic tumours using full digital mammography images. Firstly, to address the shortcomings of traditional image segmentation methods, two different deep learning methods are designed to achieve the segmentation of uterine fibroids. The deep lab model is used to optimize the lesion edge detailed information by using the void convolution algorithm and fully connected CRF, and the two semantic segmentation networks are compared to obtain the best results. The Mask RCNN case segmentation model is used to effectively extract features through the ResNet structure, combined with the RPN network to achieve effective use and fusion of features, and continuously optimize the network training to achieve a fine segmentation of the lesion area, and demonstrate the accuracy and feasibility of the two models in medical image segmentation. Histopathology was used to obtain ER, PR, HER scores, and Ki-67 percentage values for all patients. The Kaplan-Meier method was used for survival estimation, the Log-rank test was used for single-factor analysis, and Cox proportional risk regression was used for multifactor analysis. The prognostic value of each factor was calculated, as well as the factors affecting progression-free survival. This study was done to compare the imaging characteristics and diagnostic value of mammography and colour Doppler ultrasonography in nonspecific mastitis, improve the understanding of the imaging characteristics of nonspecific mastitis in these two examinations, improve the accuracy of the diagnosis of this type of disease, improve the ability of distinguishing it from breast cancer, and reduce the rate of misdiagnosis.
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spelling pubmed-78781002021-02-19 Microscopic Tumour Classification by Digital Mammography Yang, Jingjing Li, Huichao Shi, Ning Zhang, Qifan Liu, Yanan J Healthc Eng Research Article In this paper, we investigate the classification of microscopic tumours using full digital mammography images. Firstly, to address the shortcomings of traditional image segmentation methods, two different deep learning methods are designed to achieve the segmentation of uterine fibroids. The deep lab model is used to optimize the lesion edge detailed information by using the void convolution algorithm and fully connected CRF, and the two semantic segmentation networks are compared to obtain the best results. The Mask RCNN case segmentation model is used to effectively extract features through the ResNet structure, combined with the RPN network to achieve effective use and fusion of features, and continuously optimize the network training to achieve a fine segmentation of the lesion area, and demonstrate the accuracy and feasibility of the two models in medical image segmentation. Histopathology was used to obtain ER, PR, HER scores, and Ki-67 percentage values for all patients. The Kaplan-Meier method was used for survival estimation, the Log-rank test was used for single-factor analysis, and Cox proportional risk regression was used for multifactor analysis. The prognostic value of each factor was calculated, as well as the factors affecting progression-free survival. This study was done to compare the imaging characteristics and diagnostic value of mammography and colour Doppler ultrasonography in nonspecific mastitis, improve the understanding of the imaging characteristics of nonspecific mastitis in these two examinations, improve the accuracy of the diagnosis of this type of disease, improve the ability of distinguishing it from breast cancer, and reduce the rate of misdiagnosis. Hindawi 2021-02-04 /pmc/articles/PMC7878100/ /pubmed/33613927 http://dx.doi.org/10.1155/2021/6635947 Text en Copyright © 2021 Jingjing Yang et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Yang, Jingjing
Li, Huichao
Shi, Ning
Zhang, Qifan
Liu, Yanan
Microscopic Tumour Classification by Digital Mammography
title Microscopic Tumour Classification by Digital Mammography
title_full Microscopic Tumour Classification by Digital Mammography
title_fullStr Microscopic Tumour Classification by Digital Mammography
title_full_unstemmed Microscopic Tumour Classification by Digital Mammography
title_short Microscopic Tumour Classification by Digital Mammography
title_sort microscopic tumour classification by digital mammography
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878100/
https://www.ncbi.nlm.nih.gov/pubmed/33613927
http://dx.doi.org/10.1155/2021/6635947
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