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Impaired brain fractalkine-CX3CR1 signaling is implicated in cognitive dysfunction in diet-induced obese mice

INTRODUCTION: A diet high in saturated fat is well known to affect neuronal function and contribute to cognitive decline in experimental animals and humans. Fractalkine released from neurons acts on its receptor, CX3C chemokine receptor 1 (CX3CR1), in the microglia to regulate several brain function...

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Detalles Bibliográficos
Autores principales:	Kawamura, Namiko, Katsuura, Goro, Yamada-Goto, Nobuko, Novianti, Ela, Inui, Akio, Asakawa, Akihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Obesity Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878130/ https://www.ncbi.nlm.nih.gov/pubmed/33568358 http://dx.doi.org/10.1136/bmjdrc-2020-001492

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