TGFβ drives NK cell metabolic dysfunction in human metastatic breast cancer

BACKGROUND: Natural killer (NK) cells provide important immune protection from cancer and are a key requirement for particular immunotherapies. There is accumulating evidence that NK cells become dysfunctional during cancer. Overcoming NK cell exhaustion would be an important step to allow them to f...

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Detalles Bibliográficos
Autores principales: Slattery, Karen, Woods, Elena, Zaiatz-Bittencourt, Vanessa, Marks, Sam, Chew, Sonya, Conroy, Michael, Goggin, Caitriona, MacEochagain, Colm, Kennedy, John, Lucas, Sophie, Finlay, David K, Gardiner, Clair M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878131/
https://www.ncbi.nlm.nih.gov/pubmed/33568351
http://dx.doi.org/10.1136/jitc-2020-002044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878131/
https://www.ncbi.nlm.nih.gov/pubmed/33568351
http://dx.doi.org/10.1136/jitc-2020-002044

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