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G9a controls pluripotent-like identity and tumor-initiating function in human colorectal cancer

Colorectal tumors are hierarchically organized and governed by populations of self-renewing cancer stem cells, representing one of the deadliest types of cancers worldwide. Emergence of cancer stemness phenotype depends on epigenetic reprogramming, associated with profound transcriptional changes. A...

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Detalles Bibliográficos
Autores principales: Bergin, Christopher J., Zouggar, Aïcha, Haebe, Joshua R., Masibag, Angelique N., Desrochers, François M., Reilley, Simon Y., Agrawal, Gautam, Benoit, Yannick D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878189/
https://www.ncbi.nlm.nih.gov/pubmed/33323965
http://dx.doi.org/10.1038/s41388-020-01591-7