Cargando…
G9a controls pluripotent-like identity and tumor-initiating function in human colorectal cancer
Colorectal tumors are hierarchically organized and governed by populations of self-renewing cancer stem cells, representing one of the deadliest types of cancers worldwide. Emergence of cancer stemness phenotype depends on epigenetic reprogramming, associated with profound transcriptional changes. A...
Autores principales: | Bergin, Christopher J., Zouggar, Aïcha, Haebe, Joshua R., Masibag, Angelique N., Desrochers, François M., Reilley, Simon Y., Agrawal, Gautam, Benoit, Yannick D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878189/ https://www.ncbi.nlm.nih.gov/pubmed/33323965 http://dx.doi.org/10.1038/s41388-020-01591-7 |
Ejemplares similares
-
Pharmacological targeting of Sam68 functions in colorectal cancer stem cells
por: Masibag, Angelique N., et al.
Publicado: (2021) -
Intestinal Microbiota Influences DNA Methylome and Susceptibility to Colorectal Cancer
por: Zouggar, Aïcha, et al.
Publicado: (2020) -
Emerging role of G9a in cancer stemness and promises as a therapeutic target
por: Haebe, Joshua R., et al.
Publicado: (2021) -
G9a Is SETting the Stage for Colorectal Oncogenesis
por: Bergin, Christopher J., et al.
Publicado: (2020) -
Protocol for serial organoid formation assay using primary colorectal cancer tissues to evaluate cancer stem cell activity
por: Bergin, Christopher J., et al.
Publicado: (2022)