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Alopecia in Harlequin mutant mice is associated with reduced AIF protein levels and expression of retroviral elements
We investigated the contribution of apoptosis-inducing factor (AIF), a key regulator of mitochondrial biogenesis, in supporting hair growth. We report that pelage abnormalities developed during hair follicle (HF) morphogenesis in Harlequin (Hq) mutant mice. Fragility of the hair cortex was associate...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878237/ https://www.ncbi.nlm.nih.gov/pubmed/33367954 http://dx.doi.org/10.1007/s00335-020-09854-0 |