CK2 Inhibits TIMELESS Nuclear Export and Modulates CLOCK Transcriptional Activity to Regulate Circadian Rhythms

Circadian clocks orchestrate daily rhythms in organismal physiology and behavior to promote optimal performance and fitness. In Drosophila, key pacemaker proteins PERIOD (PER) and TIMELESS (TIM) are progressively phosphorylated to perform phase-specific functions. Whereas PER phosphorylation has bee...

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Detalles Bibliográficos
Autores principales: Cai, Yao D., Xue, Yongbo, Truong, Cindy C., Del Carmen-Li, Jose, Ochoa, Christopher, Vanselow, Jens T., Murphy, Katherine A., Li, Ying H., Liu, Xianhui, Kunimoto, Ben L., Zheng, Haiyan, Zhao, Caifeng, Zhang, Yong, Schlosser, Andreas, Chiu, Joanna C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878342/
https://www.ncbi.nlm.nih.gov/pubmed/33217322
http://dx.doi.org/10.1016/j.cub.2020.10.061

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