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Regulatory inter-domain interactions influence Hsp70 recruitment to the DnaJB8 chaperone
The Hsp40/Hsp70 chaperone families combine versatile folding capacity with high substrate specificity, which is mainly facilitated by Hsp40s. The structure and function of many Hsp40s remain poorly understood, particularly oligomeric Hsp40s that suppress protein aggregation. Here, we used a combinat...
Autores principales: | Ryder, Bryan D., Matlahov, Irina, Bali, Sofia, Vaquer-Alicea, Jaime, van der Wel, Patrick C. A., Joachimiak, Lukasz A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878476/ https://www.ncbi.nlm.nih.gov/pubmed/33574241 http://dx.doi.org/10.1038/s41467-021-21147-x |
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