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Mapping of susceptible variants for cold medicine-related Stevens–Johnson syndrome by whole-genome resequencing
Stevens–Johnson syndrome (SJS) and its severe condition with extensive skin detachment and a poor prognosis, toxic epidermal necrolysis (TEN), are immunologically mediated severe cutaneous reactions of the skin and mucous membranes such as the ocular surface. Genetic variations on the HLA-A and othe...
Autores principales: | Kawai, Yosuke, Hitomi, Yuki, Ueta, Mayumi, Khor, Seik-Soon, Nakatani, Ken, Sotozono, Chie, Kinoshita, Shigeru, Nagasaki, Masao, Tokunaga, Katsushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878485/ https://www.ncbi.nlm.nih.gov/pubmed/33574277 http://dx.doi.org/10.1038/s41525-021-00171-2 |
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