Alterations of 5-hydroxymethylation in circulating cell-free DNA reflect molecular distinctions of subtypes of non-Hodgkin lymphoma

The 5-methylcytosines (5mC) have been implicated in the pathogenesis of diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL). However, the role of 5-hydroxymethylcytosines (5hmC) that are generated from 5mC through active demethylation, in lymphomagenesis is unknown. We profiled genome...

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Detalles Bibliográficos
Autores principales: Chiu, Brian C.-H., Chen, Chang, You, Qiancheng, Chiu, Rudyard, Venkataraman, Girish, Zeng, Chang, Zhang, Zhou, Cui, Xiaolong, Smith, Sonali M., He, Chuan, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878492/
https://www.ncbi.nlm.nih.gov/pubmed/33574286
http://dx.doi.org/10.1038/s41525-021-00179-8

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