Neutrophil Extracellular Traps Tied to Rheumatoid Arthritis: Points to Ponder

In recent years, neutrophil extracellular traps at the forefront of neutrophil biology have proven to help capture and kill pathogens involved in the inflammatory process. There is growing evidence that persistent neutrophil extracellular traps drive the pathogenesis of autoimmune diseases. In this...

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Autores principales: Song, Wenpeng, Ye, Jing, Pan, Nanfang, Tan, Chunyu, Herrmann, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878527/
https://www.ncbi.nlm.nih.gov/pubmed/33584645
http://dx.doi.org/10.3389/fimmu.2020.578129
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author Song, Wenpeng
Ye, Jing
Pan, Nanfang
Tan, Chunyu
Herrmann, Martin
author_facet Song, Wenpeng
Ye, Jing
Pan, Nanfang
Tan, Chunyu
Herrmann, Martin
author_sort Song, Wenpeng
collection PubMed
description In recent years, neutrophil extracellular traps at the forefront of neutrophil biology have proven to help capture and kill pathogens involved in the inflammatory process. There is growing evidence that persistent neutrophil extracellular traps drive the pathogenesis of autoimmune diseases. In this paper, we summarize the potential of neutrophil extracellular traps to drive the pathogenesis of rheumatoid arthritis and experimental animal models. We also describe the diagnosis and treatment of rheumatoid arthritis in association with neutrophil extracellular traps.
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spelling pubmed-78785272021-02-13 Neutrophil Extracellular Traps Tied to Rheumatoid Arthritis: Points to Ponder Song, Wenpeng Ye, Jing Pan, Nanfang Tan, Chunyu Herrmann, Martin Front Immunol Immunology In recent years, neutrophil extracellular traps at the forefront of neutrophil biology have proven to help capture and kill pathogens involved in the inflammatory process. There is growing evidence that persistent neutrophil extracellular traps drive the pathogenesis of autoimmune diseases. In this paper, we summarize the potential of neutrophil extracellular traps to drive the pathogenesis of rheumatoid arthritis and experimental animal models. We also describe the diagnosis and treatment of rheumatoid arthritis in association with neutrophil extracellular traps. Frontiers Media S.A. 2021-01-29 /pmc/articles/PMC7878527/ /pubmed/33584645 http://dx.doi.org/10.3389/fimmu.2020.578129 Text en Copyright © 2021 Song, Ye, Pan, Tan and Herrmann http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Song, Wenpeng
Ye, Jing
Pan, Nanfang
Tan, Chunyu
Herrmann, Martin
Neutrophil Extracellular Traps Tied to Rheumatoid Arthritis: Points to Ponder
title Neutrophil Extracellular Traps Tied to Rheumatoid Arthritis: Points to Ponder
title_full Neutrophil Extracellular Traps Tied to Rheumatoid Arthritis: Points to Ponder
title_fullStr Neutrophil Extracellular Traps Tied to Rheumatoid Arthritis: Points to Ponder
title_full_unstemmed Neutrophil Extracellular Traps Tied to Rheumatoid Arthritis: Points to Ponder
title_short Neutrophil Extracellular Traps Tied to Rheumatoid Arthritis: Points to Ponder
title_sort neutrophil extracellular traps tied to rheumatoid arthritis: points to ponder
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878527/
https://www.ncbi.nlm.nih.gov/pubmed/33584645
http://dx.doi.org/10.3389/fimmu.2020.578129
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AT yejing neutrophilextracellulartrapstiedtorheumatoidarthritispointstoponder
AT pannanfang neutrophilextracellulartrapstiedtorheumatoidarthritispointstoponder
AT tanchunyu neutrophilextracellulartrapstiedtorheumatoidarthritispointstoponder
AT herrmannmartin neutrophilextracellulartrapstiedtorheumatoidarthritispointstoponder

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