Rhabdomyosarcoma Cells Produce Their Own Extracellular Matrix With Minimal Involvement of Cancer-Associated Fibroblasts: A Preliminary Study

BACKGROUND: The interplay between neoplastic cells and surrounding extracellular matrix (ECM) is one of the determinant elements for cancer growth. The remodeling of the ECM by cancer-associated fibroblasts (CAFs) shapes tumor microenvironment by depositing and digesting ECM proteins, hence promotin...

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Detalles Bibliográficos
Autores principales: D’Agostino, Stefania, Tombolan, Lucia, Saggioro, Mattia, Frasson, Chiara, Rampazzo, Elena, Pellegrini, Stefania, Favaretto, Francesca, Biz, Carlo, Ruggieri, Pietro, Gamba, Piergiorgio, Bonvini, Paolo, Aveic, Sanja, Giovannoni, Roberto, Pozzobon, Michela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878542/
https://www.ncbi.nlm.nih.gov/pubmed/33585217
http://dx.doi.org/10.3389/fonc.2020.600980

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