Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling

Natural mitochondrial DNA (mtDNA) mutations enable the inference of clonal relationships among cells. mtDNA can be profiled along with measures of cell state, but has not yet been combined with the massively parallel approaches needed to tackle the complexity of human tissue. Here, we introduce a hi...

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Detalles Bibliográficos
Autores principales: Lareau, Caleb A., Ludwig, Leif S., Muus, Christoph, Gohil, Satyen H., Zhao, Tongtong, Chiang, Zachary, Pelka, Karin, Verboon, Jeffrey M., Luo, Wendy, Christian, Elena, Rosebrock, Daniel, Getz, Gad, Boland, Genevieve M., Chen, Fei, Buenrostro, Jason D., Hacohen, Nir, Wu, Catherine J., Aryee, Martin J., Regev, Aviv, Sankaran, Vijay G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878580/
https://www.ncbi.nlm.nih.gov/pubmed/32788668
http://dx.doi.org/10.1038/s41587-020-0645-6

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