Dynamic Regulation of JAK-STAT Signaling Through the Prolactin Receptor Predicted by Computational Modeling

INTRODUCTION: The expansion of insulin-producing beta cells during pregnancy is critical to maintain glucose homeostasis in the face of increasing insulin resistance. Prolactin receptor (PRLR) signaling is one of the primary mediators of beta cell expansion during pregnancy, and loss of PRLR signali...

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Detalles Bibliográficos
Autores principales: Mortlock, Ryland D., Georgia, Senta K., Finley, Stacey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878662/
https://www.ncbi.nlm.nih.gov/pubmed/33633812
http://dx.doi.org/10.1007/s12195-020-00647-8

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