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Dual Inhibition of γ-Tubulin and Plk1 Induces Mitotic Cell Death

α/β-Tubulin inhibitors that alter microtubule (MT) dynamics are commonly used in cancer therapy, however, these inhibitors also cause severe side effects such as peripheral neuropathy. γ-Tubulin is a possible target as antitumor drugs with low side effects, but the antitumor effect of γ-tubulin inhi...

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Detalles Bibliográficos
Autores principales: Ebisu, Haruna, Shintani, Kana, Chinen, Takumi, Nagumo, Yoko, Shioda, Shuya, Hatanaka, Taisei, Sakakura, Akira, Hayakawa, Ichiro, Kigoshi, Hideo, Usui, Takeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878676/
https://www.ncbi.nlm.nih.gov/pubmed/33584305
http://dx.doi.org/10.3389/fphar.2020.620185

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