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Absence of Both Thyroid Hormone Transporters MCT8 and OATP1C1 Impairs Neural Stem Cell Fate in the Adult Mouse Subventricular Zone

Adult neural stem cell (NSC) generation in vertebrate brains requires thyroid hormones (THs). How THs enter the NSC population is unknown, although TH availability determines proliferation and neuronal versus glial progenitor determination in murine subventricular zone (SVZ) NSCs. Mice display neuro...

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Detalles Bibliográficos
Autores principales: Luongo, Cristina, Butruille, Lucile, Sébillot, Anthony, Le Blay, Karine, Schwaninger, Markus, Heuer, Heike, Demeneix, Barbara A., Remaud, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878696/
https://www.ncbi.nlm.nih.gov/pubmed/33450189
http://dx.doi.org/10.1016/j.stemcr.2020.12.009

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