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Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy
Radical prostatectomy can alter the anatomy of the urinary bladder. We aimed to evaluate bladder function before and 4 months after radical prostatectomy using the urodynamic test and overactive bladder (OAB) symptom score. Among 70 prospectively enrolled patients, 61 patients completed the study. I...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878735/ https://www.ncbi.nlm.nih.gov/pubmed/33574414 http://dx.doi.org/10.1038/s41598-021-83143-x |
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author | Lee, Dong Sup Lee, Seung-ju |
author_facet | Lee, Dong Sup Lee, Seung-ju |
author_sort | Lee, Dong Sup |
collection | PubMed |
description | Radical prostatectomy can alter the anatomy of the urinary bladder. We aimed to evaluate bladder function before and 4 months after radical prostatectomy using the urodynamic test and overactive bladder (OAB) symptom score. Among 70 prospectively enrolled patients, 61 patients completed the study. In the urodynamic test, bladder capacity and compliance did not change, the frequency of involuntary detrusor contraction decreased, the maximum flow rate and bladder outlet obstruction index improved, and the maximum urethral closure pressure (MUCP) deteriorated. Further evaluation of urodynamic parameters according to changes in symptoms was made. Although change in bladder compliance was correlated with changes in OAB symptoms, not the relative change of bladder compliance but the relative change in the MUCP was reliable factor when OAB symptoms were deteriorated. In general, prostatectomy did not deteriorate the condition of the detrusor; rather, change in the MUCP could be responsible for postprostatectomy OAB. |
format | Online Article Text |
id | pubmed-7878735 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-78787352021-02-12 Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy Lee, Dong Sup Lee, Seung-ju Sci Rep Article Radical prostatectomy can alter the anatomy of the urinary bladder. We aimed to evaluate bladder function before and 4 months after radical prostatectomy using the urodynamic test and overactive bladder (OAB) symptom score. Among 70 prospectively enrolled patients, 61 patients completed the study. In the urodynamic test, bladder capacity and compliance did not change, the frequency of involuntary detrusor contraction decreased, the maximum flow rate and bladder outlet obstruction index improved, and the maximum urethral closure pressure (MUCP) deteriorated. Further evaluation of urodynamic parameters according to changes in symptoms was made. Although change in bladder compliance was correlated with changes in OAB symptoms, not the relative change of bladder compliance but the relative change in the MUCP was reliable factor when OAB symptoms were deteriorated. In general, prostatectomy did not deteriorate the condition of the detrusor; rather, change in the MUCP could be responsible for postprostatectomy OAB. Nature Publishing Group UK 2021-02-11 /pmc/articles/PMC7878735/ /pubmed/33574414 http://dx.doi.org/10.1038/s41598-021-83143-x Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Lee, Dong Sup Lee, Seung-ju Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy |
title | Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy |
title_full | Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy |
title_fullStr | Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy |
title_full_unstemmed | Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy |
title_short | Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy |
title_sort | urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878735/ https://www.ncbi.nlm.nih.gov/pubmed/33574414 http://dx.doi.org/10.1038/s41598-021-83143-x |
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