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Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy

Radical prostatectomy can alter the anatomy of the urinary bladder. We aimed to evaluate bladder function before and 4 months after radical prostatectomy using the urodynamic test and overactive bladder (OAB) symptom score. Among 70 prospectively enrolled patients, 61 patients completed the study. I...

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Detalles Bibliográficos
Autores principales: Lee, Dong Sup, Lee, Seung-ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878735/
https://www.ncbi.nlm.nih.gov/pubmed/33574414
http://dx.doi.org/10.1038/s41598-021-83143-x
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author Lee, Dong Sup
Lee, Seung-ju
author_facet Lee, Dong Sup
Lee, Seung-ju
author_sort Lee, Dong Sup
collection PubMed
description Radical prostatectomy can alter the anatomy of the urinary bladder. We aimed to evaluate bladder function before and 4 months after radical prostatectomy using the urodynamic test and overactive bladder (OAB) symptom score. Among 70 prospectively enrolled patients, 61 patients completed the study. In the urodynamic test, bladder capacity and compliance did not change, the frequency of involuntary detrusor contraction decreased, the maximum flow rate and bladder outlet obstruction index improved, and the maximum urethral closure pressure (MUCP) deteriorated. Further evaluation of urodynamic parameters according to changes in symptoms was made. Although change in bladder compliance was correlated with changes in OAB symptoms, not the relative change of bladder compliance but the relative change in the MUCP was reliable factor when OAB symptoms were deteriorated. In general, prostatectomy did not deteriorate the condition of the detrusor; rather, change in the MUCP could be responsible for postprostatectomy OAB.
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spelling pubmed-78787352021-02-12 Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy Lee, Dong Sup Lee, Seung-ju Sci Rep Article Radical prostatectomy can alter the anatomy of the urinary bladder. We aimed to evaluate bladder function before and 4 months after radical prostatectomy using the urodynamic test and overactive bladder (OAB) symptom score. Among 70 prospectively enrolled patients, 61 patients completed the study. In the urodynamic test, bladder capacity and compliance did not change, the frequency of involuntary detrusor contraction decreased, the maximum flow rate and bladder outlet obstruction index improved, and the maximum urethral closure pressure (MUCP) deteriorated. Further evaluation of urodynamic parameters according to changes in symptoms was made. Although change in bladder compliance was correlated with changes in OAB symptoms, not the relative change of bladder compliance but the relative change in the MUCP was reliable factor when OAB symptoms were deteriorated. In general, prostatectomy did not deteriorate the condition of the detrusor; rather, change in the MUCP could be responsible for postprostatectomy OAB. Nature Publishing Group UK 2021-02-11 /pmc/articles/PMC7878735/ /pubmed/33574414 http://dx.doi.org/10.1038/s41598-021-83143-x Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Lee, Dong Sup
Lee, Seung-ju
Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy
title Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy
title_full Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy
title_fullStr Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy
title_full_unstemmed Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy
title_short Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy
title_sort urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878735/
https://www.ncbi.nlm.nih.gov/pubmed/33574414
http://dx.doi.org/10.1038/s41598-021-83143-x
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