Direct reprogramming of oligodendrocyte precursor cells into GABAergic inhibitory neurons by a single homeodomain transcription factor Dlx2

Oligodendrocyte precursor cells (NG2 glia) are uniformly distributed proliferative cells in the mammalian central nervous system and generate myelinating oligodendrocytes throughout life. A subpopulation of OPCs in the neocortex arises from progenitor cells in the embryonic ganglionic eminences that...

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Detalles Bibliográficos
Autores principales: Boshans, Linda L., Soh, Heun, Wood, William M., Nolan, Timothy M., Mandoiu, Ion I., Yanagawa, Yuchio, Tzingounis, Anastasios V., Nishiyama, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878775/
https://www.ncbi.nlm.nih.gov/pubmed/33574458
http://dx.doi.org/10.1038/s41598-021-82931-9

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