GWAS for autoimmune Addison’s disease identifies multiple risk loci and highlights AIRE in disease susceptibility

Autoimmune Addison’s disease (AAD) is characterized by the autoimmune destruction of the adrenal cortex. Low prevalence and complex inheritance have long hindered successful genetic studies. We here report the first genome-wide association study on AAD, which identifies nine independent risk loci (P...

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Detalles Bibliográficos
Autores principales: Eriksson, Daniel, Røyrvik, Ellen Christine, Aranda-Guillén, Maribel, Berger, Amund Holte, Landegren, Nils, Artaza, Haydee, Hallgren, Åsa, Grytaas, Marianne Aardal, Ström, Sara, Bratland, Eirik, Botusan, Ileana Ruxandra, Oftedal, Bergithe Eikeland, Breivik, Lars, Vaudel, Marc, Helgeland, Øyvind, Falorni, Alberto, Jørgensen, Anders Palmstrøm, Hulting, Anna-Lena, Svartberg, Johan, Ekwall, Olov, Fougner, Kristian Johan, Wahlberg, Jeanette, Nedrebø, Bjørn Gunnar, Dahlqvist, Per, Knappskog, Per Morten, Wolff, Anette Susanne Bøe, Bensing, Sophie, Johansson, Stefan, Kämpe, Olle, Husebye, Eystein Sverre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878795/
https://www.ncbi.nlm.nih.gov/pubmed/33574239
http://dx.doi.org/10.1038/s41467-021-21015-8

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