Structural mechanism of bivalent histone H3K4me3K9me3 recognition by the Spindlin1/C11orf84 complex in rRNA transcription activation

Spindlin1 is a unique multivalent epigenetic reader that facilitates ribosomal RNA transcription. In this study, we provide molecular and structural basis by which Spindlin1 acts in complex with C11orf84 to preferentially recognize non-canonical bivalent mark of trimethylated lysine 4 and lysine 9 p...

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Detalles Bibliográficos
Autores principales: Du, Yongming, Yan, Yinxia, Xie, Si, Huang, Hao, Wang, Xin, Ng, Ray Kit, Zhou, Ming-Ming, Qian, Chengmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878818/
https://www.ncbi.nlm.nih.gov/pubmed/33574238
http://dx.doi.org/10.1038/s41467-021-21236-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878818/
https://www.ncbi.nlm.nih.gov/pubmed/33574238
http://dx.doi.org/10.1038/s41467-021-21236-x

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