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Depletion of Trp53 and Cdkn2a Does Not Promote Self-Renewal in the Mammary Gland but Amplifies Proliferation Induced by TNF-α

The mammary epithelium undergoes several rounds of extensive proliferation during the female reproductive cycle. Its expansion is a tightly regulated process, fueled by the mammary stem cells and these cells' unique property of self-renewal. Sufficient new cells have to be produced to maintain...

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Detalles Bibliográficos
Autores principales:	van Weele, Linda J., Scheeren, Ferenc A., Cai, Shang, Kuo, Angera H., Qian, Dalong, Ho, William H.D., Clarke, Michael F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878826/ https://www.ncbi.nlm.nih.gov/pubmed/33482103 http://dx.doi.org/10.1016/j.stemcr.2020.12.012

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