Gastruloid Development Competence Discriminates Different States of Pluripotency

Floating spheroidal aggregates of mouse embryonic stem cells can develop into polarized/elongated organoids, namely gastruloids. We set up a high-performing assay to measure gastruloid formation efficiency (GFE), and found that GFE decreases as pluripotency progresses from naive (GFE ≥ 95%) to prime...

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Detalles Bibliográficos
Autores principales: Cermola, Federica, D'Aniello, Cristina, Tatè, Rosarita, De Cesare, Dario, Martinez-Arias, Alfonso, Minchiotti, Gabriella, Patriarca, Eduardo Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878839/
https://www.ncbi.nlm.nih.gov/pubmed/33482102
http://dx.doi.org/10.1016/j.stemcr.2020.12.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878839/
https://www.ncbi.nlm.nih.gov/pubmed/33482102
http://dx.doi.org/10.1016/j.stemcr.2020.12.013

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