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Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase
Aspartate transcarbamoylase (ATC), an essential enzyme for de novo pyrimidine biosynthesis, is uniquely regulated in plants by feedback inhibition of uridine 5-monophosphate (UMP). Despite its importance in plant growth, the structure of this UMP-controlled ATC and the regulatory mechanism remain un...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878868/ https://www.ncbi.nlm.nih.gov/pubmed/33574254 http://dx.doi.org/10.1038/s41467-021-21165-9 |