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Compliance with D2 lymph node dissection in reduced-port totally laparoscopic distal gastrectomy in patients with gastric cancer

This phase II clinical trial was performed to determine whether reduced-port laparoscopic surgery with complete D2 lymph node (LN) dissection for gastric cancer is a safe and feasible surgical technique. The prospectively enrolled 65 gastric cancer patients underwent reduced-port surgery (i.e., trip...

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Autores principales: Oh, Sung Eun, Seo, Jeong Eun, An, Ji Yeong, Choi, Min-Gew, Sohn, Tae Sung, Bae, Jae Moon, Kim, Sung, Lee, Jun Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878888/
https://www.ncbi.nlm.nih.gov/pubmed/33574571
http://dx.doi.org/10.1038/s41598-021-83386-8
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author Oh, Sung Eun
Seo, Jeong Eun
An, Ji Yeong
Choi, Min-Gew
Sohn, Tae Sung
Bae, Jae Moon
Kim, Sung
Lee, Jun Ho
author_facet Oh, Sung Eun
Seo, Jeong Eun
An, Ji Yeong
Choi, Min-Gew
Sohn, Tae Sung
Bae, Jae Moon
Kim, Sung
Lee, Jun Ho
author_sort Oh, Sung Eun
collection PubMed
description This phase II clinical trial was performed to determine whether reduced-port laparoscopic surgery with complete D2 lymph node (LN) dissection for gastric cancer is a safe and feasible surgical technique. The prospectively enrolled 65 gastric cancer patients underwent reduced-port surgery (i.e., triple-incision totally laparoscopic distal gastrectomy [Duet TLDG] with D2 lymphadenectomy). Compliance rate was the primary outcome, which was defined as cases in which there was no more than one missing LN station during D2 LN dissection. The secondary outcomes were the numbers of dissected and retrieved LNs in each station and other short-term surgical outcomes and postoperative course. The compliance rate was 58.5%. The total number of retrieved LNs was 41 (range: 14–83 LNs). The most common station missing from LN retrieval was station no. 5 (35/65; 53.8%), followed by station no. 1 (24/65; 36.9%). The overall postoperative complication rate was 20.0% (13/65). One patient underwent surgical treatment for postoperative complications. There was no instances of mortality. Duet TLDG is an oncologically and technically safe surgical method of gastrectomy and D2 lymphadenectomy.
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spelling pubmed-78788882021-02-12 Compliance with D2 lymph node dissection in reduced-port totally laparoscopic distal gastrectomy in patients with gastric cancer Oh, Sung Eun Seo, Jeong Eun An, Ji Yeong Choi, Min-Gew Sohn, Tae Sung Bae, Jae Moon Kim, Sung Lee, Jun Ho Sci Rep Article This phase II clinical trial was performed to determine whether reduced-port laparoscopic surgery with complete D2 lymph node (LN) dissection for gastric cancer is a safe and feasible surgical technique. The prospectively enrolled 65 gastric cancer patients underwent reduced-port surgery (i.e., triple-incision totally laparoscopic distal gastrectomy [Duet TLDG] with D2 lymphadenectomy). Compliance rate was the primary outcome, which was defined as cases in which there was no more than one missing LN station during D2 LN dissection. The secondary outcomes were the numbers of dissected and retrieved LNs in each station and other short-term surgical outcomes and postoperative course. The compliance rate was 58.5%. The total number of retrieved LNs was 41 (range: 14–83 LNs). The most common station missing from LN retrieval was station no. 5 (35/65; 53.8%), followed by station no. 1 (24/65; 36.9%). The overall postoperative complication rate was 20.0% (13/65). One patient underwent surgical treatment for postoperative complications. There was no instances of mortality. Duet TLDG is an oncologically and technically safe surgical method of gastrectomy and D2 lymphadenectomy. Nature Publishing Group UK 2021-02-11 /pmc/articles/PMC7878888/ /pubmed/33574571 http://dx.doi.org/10.1038/s41598-021-83386-8 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Oh, Sung Eun
Seo, Jeong Eun
An, Ji Yeong
Choi, Min-Gew
Sohn, Tae Sung
Bae, Jae Moon
Kim, Sung
Lee, Jun Ho
Compliance with D2 lymph node dissection in reduced-port totally laparoscopic distal gastrectomy in patients with gastric cancer
title Compliance with D2 lymph node dissection in reduced-port totally laparoscopic distal gastrectomy in patients with gastric cancer
title_full Compliance with D2 lymph node dissection in reduced-port totally laparoscopic distal gastrectomy in patients with gastric cancer
title_fullStr Compliance with D2 lymph node dissection in reduced-port totally laparoscopic distal gastrectomy in patients with gastric cancer
title_full_unstemmed Compliance with D2 lymph node dissection in reduced-port totally laparoscopic distal gastrectomy in patients with gastric cancer
title_short Compliance with D2 lymph node dissection in reduced-port totally laparoscopic distal gastrectomy in patients with gastric cancer
title_sort compliance with d2 lymph node dissection in reduced-port totally laparoscopic distal gastrectomy in patients with gastric cancer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878888/
https://www.ncbi.nlm.nih.gov/pubmed/33574571
http://dx.doi.org/10.1038/s41598-021-83386-8
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