Procalcitonin as a biomarker for ventilator associated pneumonia in COVID-19 patients: Is it an useful stewardship tool?

Ventilator associated pneumonia(VAP) is a severe complication that can lead to high mortality when not early identified or when therapy is delayed. The aim of this study was to evaluate procalcitonin(PCT) as a biomarker for VAP development. In total, 73 hospitalized patients with COVID-19 were analy...

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Autores principales: Côrtes, Marina Farrel, de Almeida, Bianca Leal, Espinoza, Evelyn Patricia Sanchez, Campos, Aléia Faustina, do Nascimento Moura, Maria Luiza, Salomão, Matias C., Boszczowski, Icaro, Freire, Maristela Pinheiro, de Carvalho, Laina Bubach, Paranhos-Baccalà, Gláucia, Costa, Silvia Figueiredo, Guimarães, Thaís
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Clinical Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879055/
https://www.ncbi.nlm.nih.gov/pubmed/34243136
http://dx.doi.org/10.1016/j.diagmicrobio.2021.115344
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author Côrtes, Marina Farrel
de Almeida, Bianca Leal
Espinoza, Evelyn Patricia Sanchez
Campos, Aléia Faustina
do Nascimento Moura, Maria Luiza
Salomão, Matias C.
Boszczowski, Icaro
Freire, Maristela Pinheiro
de Carvalho, Laina Bubach
Paranhos-Baccalà, Gláucia
Costa, Silvia Figueiredo
Guimarães, Thaís
author_facet Côrtes, Marina Farrel
de Almeida, Bianca Leal
Espinoza, Evelyn Patricia Sanchez
Campos, Aléia Faustina
do Nascimento Moura, Maria Luiza
Salomão, Matias C.
Boszczowski, Icaro
Freire, Maristela Pinheiro
de Carvalho, Laina Bubach
Paranhos-Baccalà, Gláucia
Costa, Silvia Figueiredo
Guimarães, Thaís
author_sort Côrtes, Marina Farrel
collection PubMed
description Ventilator associated pneumonia(VAP) is a severe complication that can lead to high mortality when not early identified or when therapy is delayed. The aim of this study was to evaluate procalcitonin(PCT) as a biomarker for VAP development. In total, 73 hospitalized patients with COVID-19 were analyzed. PCT levels greater than 0.975ng/mL were more related to VAP. No association was found for C-reactive protein (CRP). The results show that procalcitonin may be a pertinent biomarker for VAP diagnosis and can be a helpful tool for antibiotic withdrawal.
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spelling pubmed-78790552021-02-16 Procalcitonin as a biomarker for ventilator associated pneumonia in COVID-19 patients: Is it an useful stewardship tool? Côrtes, Marina Farrel de Almeida, Bianca Leal Espinoza, Evelyn Patricia Sanchez Campos, Aléia Faustina do Nascimento Moura, Maria Luiza Salomão, Matias C. Boszczowski, Icaro Freire, Maristela Pinheiro de Carvalho, Laina Bubach Paranhos-Baccalà, Gláucia Costa, Silvia Figueiredo Guimarães, Thaís Diagn Microbiol Infect Dis Clinical Studies Ventilator associated pneumonia(VAP) is a severe complication that can lead to high mortality when not early identified or when therapy is delayed. The aim of this study was to evaluate procalcitonin(PCT) as a biomarker for VAP development. In total, 73 hospitalized patients with COVID-19 were analyzed. PCT levels greater than 0.975ng/mL were more related to VAP. No association was found for C-reactive protein (CRP). The results show that procalcitonin may be a pertinent biomarker for VAP diagnosis and can be a helpful tool for antibiotic withdrawal. Elsevier Inc. 2021-10 2021-02-12 /pmc/articles/PMC7879055/ /pubmed/34243136 http://dx.doi.org/10.1016/j.diagmicrobio.2021.115344 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Clinical Studies
Côrtes, Marina Farrel
de Almeida, Bianca Leal
Espinoza, Evelyn Patricia Sanchez
Campos, Aléia Faustina
do Nascimento Moura, Maria Luiza
Salomão, Matias C.
Boszczowski, Icaro
Freire, Maristela Pinheiro
de Carvalho, Laina Bubach
Paranhos-Baccalà, Gláucia
Costa, Silvia Figueiredo
Guimarães, Thaís
Procalcitonin as a biomarker for ventilator associated pneumonia in COVID-19 patients: Is it an useful stewardship tool?
title Procalcitonin as a biomarker for ventilator associated pneumonia in COVID-19 patients: Is it an useful stewardship tool?
title_full Procalcitonin as a biomarker for ventilator associated pneumonia in COVID-19 patients: Is it an useful stewardship tool?
title_fullStr Procalcitonin as a biomarker for ventilator associated pneumonia in COVID-19 patients: Is it an useful stewardship tool?
title_full_unstemmed Procalcitonin as a biomarker for ventilator associated pneumonia in COVID-19 patients: Is it an useful stewardship tool?
title_short Procalcitonin as a biomarker for ventilator associated pneumonia in COVID-19 patients: Is it an useful stewardship tool?
title_sort procalcitonin as a biomarker for ventilator associated pneumonia in covid-19 patients: is it an useful stewardship tool?
topic Clinical Studies
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879055/
https://www.ncbi.nlm.nih.gov/pubmed/34243136
http://dx.doi.org/10.1016/j.diagmicrobio.2021.115344
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