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Structural insight reveals SARS-CoV-2 ORF7a as an immunomodulating factor for human CD14(+) monocytes

Dysregulated immune cell responses have been linked to the severity of coronavirus disease 2019 (COVID-19), but the specific viral factors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were currently unknown. Herein, we reveal that the Immunoglobulin-like fold ectodomain of the vir...

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Detalles Bibliográficos
Autores principales:	Zhou, Ziliang, Huang, Chunliu, Zhou, Zhechong, Huang, Zhaoxia, Su, Lili, Kang, Sisi, Chen, Xiaoxue, Chen, Qiuyue, He, Suhua, Rong, Xia, Xiao, Fei, Chen, Jun, Chen, Shoudeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879101/ https://www.ncbi.nlm.nih.gov/pubmed/33615195 http://dx.doi.org/10.1016/j.isci.2021.102187

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