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Glomerular Complement Factor H–Related Protein 5 is Associated with Histologic Injury in Immunoglobulin A Nephropathy

INTRODUCTION: Immunoglobulin A nephrology (IgAN), characterized by co-deposition of IgA and complement components, is an activation of complement system involved disease. Factor H–related protein 5 (FHR-5) antagonized the ability of factor H to negatively regulate C3 activation, which leads to overa...

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Detalles Bibliográficos
Autores principales:	Guo, Wei-yi, Sun, Li-jun, Dong, Hong-rui, Wang, Guo-qin, Xu, Xiao-yi, Zhao, Zhi-rui, Cheng, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Clinical Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879122/ https://www.ncbi.nlm.nih.gov/pubmed/33615066 http://dx.doi.org/10.1016/j.ekir.2020.11.019

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