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Truly epigenetic: A centromere finds a “neo” home
Murillo-Pineda and colleagues (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202007210) use CRISPR-Cas9–based genetic engineering in human cells to induce a new functional centromere at a naive chromosomal site. Long-read DNA sequencing at the neocentromere provides firm evidence that centromere e...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879491/ https://www.ncbi.nlm.nih.gov/pubmed/33566070 http://dx.doi.org/10.1083/jcb.202101027 |
| _version_ | 1783650526708105216 |
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| author | Carty, Ben L. Dunleavy, Elaine M. |
| author_facet | Carty, Ben L. Dunleavy, Elaine M. |
| author_sort | Carty, Ben L. |
| collection | PubMed |
| description | Murillo-Pineda and colleagues (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202007210) use CRISPR-Cas9–based genetic engineering in human cells to induce a new functional centromere at a naive chromosomal site. Long-read DNA sequencing at the neocentromere provides firm evidence that centromere establishment is a truly epigenetic event. |
| format | Online Article Text |
| id | pubmed-7879491 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Rockefeller University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-78794912021-09-01 Truly epigenetic: A centromere finds a “neo” home Carty, Ben L. Dunleavy, Elaine M. J Cell Biol Spotlight Murillo-Pineda and colleagues (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202007210) use CRISPR-Cas9–based genetic engineering in human cells to induce a new functional centromere at a naive chromosomal site. Long-read DNA sequencing at the neocentromere provides firm evidence that centromere establishment is a truly epigenetic event. Rockefeller University Press 2021-02-10 /pmc/articles/PMC7879491/ /pubmed/33566070 http://dx.doi.org/10.1083/jcb.202101027 Text en © 2021 Carty and Dunleavy http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). |
| spellingShingle | Spotlight Carty, Ben L. Dunleavy, Elaine M. Truly epigenetic: A centromere finds a “neo” home |
| title | Truly epigenetic: A centromere finds a “neo” home |
| title_full | Truly epigenetic: A centromere finds a “neo” home |
| title_fullStr | Truly epigenetic: A centromere finds a “neo” home |
| title_full_unstemmed | Truly epigenetic: A centromere finds a “neo” home |
| title_short | Truly epigenetic: A centromere finds a “neo” home |
| title_sort | truly epigenetic: a centromere finds a “neo” home |
| topic | Spotlight |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879491/ https://www.ncbi.nlm.nih.gov/pubmed/33566070 http://dx.doi.org/10.1083/jcb.202101027 |
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