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Truly epigenetic: A centromere finds a “neo” home
Murillo-Pineda and colleagues (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202007210) use CRISPR-Cas9–based genetic engineering in human cells to induce a new functional centromere at a naive chromosomal site. Long-read DNA sequencing at the neocentromere provides firm evidence that centromere e...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Rockefeller University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879491/ https://www.ncbi.nlm.nih.gov/pubmed/33566070 http://dx.doi.org/10.1083/jcb.202101027 |