Investigation of association of genetic variant rs3918242 of matrix metalloproteinase-9 with hypertension, myocardial infarction and progression of ventricular dysfunction in Irish Caucasian patients with diabetes: a report from the STOP-HF follow-up programme

BACKGROUND: Hypertension and/or myocardial infarction are common causes of heart failure in Type 2 diabetes. Progression to heart failure is usually preceded by ventricular dysfunction, linked to matrix metalloproteinase (MMP) mediated extracellular matrix changes. We hypothesise that the minor alle...

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Detalles Bibliográficos
Autores principales: Watson, Chris, Spiers, J. Paul, Waterstone, Max, Russell-Hallinan, Adam, Gallagher, Joseph, McDonald, Kenneth, Ryan, Cristin, Gilmer, John, Ledwidge, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879511/
https://www.ncbi.nlm.nih.gov/pubmed/33579197
http://dx.doi.org/10.1186/s12872-021-01860-7

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