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Use of a small DNA virus model to investigate mechanisms of CpG dinucleotide-induced attenuation of virus replication
Suppression of the CpG dinucleotide is widespread in RNA viruses infecting vertebrates and plants, and in the genomes of retroviruses and small mammalian DNA viruses. The functional basis for CpG suppression in the latter was investigated through the construction of mutants of the parvovirus, minute...
Autores principales: | Loew, Lisa, Goonawardane, Niluka, Ratcliff, Jeremy, Nguyen, Dung, Simmonds, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879557/ https://www.ncbi.nlm.nih.gov/pubmed/32783803 http://dx.doi.org/10.1099/jgv.0.001477 |
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